This is another comparatively small family, with 8 genera and about 76 described species, which occur primarily in the New World. Exceptions are the genera Nebo, found in Syria, Jordan, Lebanon, Israel, Egypt (Sinai), Saudi Arabia, Yemen, and Oman, and two species of Heteronebo, both known from the island of Abd-el-Kuri (Yemen). Oddly, the other 12 species of Heteronebo are found on various islands in the Caribbean, along with the genera Oiclus and Cazierius and most of the species in the genus Didymocentrus. Didymocentrus is also represented in Honduras, El Salvador, Nicaragua, and Costa Rica. Another genus, Tarsoporosus, is found in Venezuela and Colombia. The genus Bioculus is endemic to Baja California Sur, Mexico, and its associated islands. Widespread through Honduras, Guatemala, Belize, and Mexico, Diploeentrus, with approximately 34 described species, is the largest genus in the family. Five species occur in the southern parts of Arizona, New Mexico, and Texas. Diplocentrids are not generally considered dangerous. However, stings from the Middle Eastern species, Nebo hierichonticus, may cause mild, local hemorrhages and slight necrosis.

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