Generalized Microfluidic Chip

A microfluidic chip is a plate of silica, glass or plastic trenched with narrow channels through which samples flow in tiny streams. Blood, bacterial suspensions, and solutions of proteins and buffers flow within the channels. Architectures of the channels and chips vary. Channels may be open or closed, and the walls are coated with substances that extract molecules from solution. Only molecules touching the walls can be extracted, and most fluid and solute flows unimpeded along the centers of the channels. Currently, devices measure diffusion coefficients, viscosities, pH, reaction kinetics and other modalities. Molecules cross walls bidirectionally as hemolymph gives up or receives molecules for cells residing on, beneath or in the surfaces. Both chips and hemo-coels rely on surface-to-volume ratios for extractions.

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