1. Cytochromes P450 are a group of oxidizing enzymes. What characteristic metal-co-ordinated group do they share? When acting on exogenous compounds (natural or synthetic compounds from outside the body) do cytochromes convert them to more lipid-soluble, or water-soluble compounds?

2. Write and balance the reaction between acetone and NADH and H+.

3. Complete a balanced equation for the reaction between butyric acid and FAD.

4. Show a scheme for the reaction between thiamine diphosphate, lipoic acid and a-keto-isovaleric acid (structure in Figure 3.12).

5. What is the product of the reaction between hexanoic acid and S-adenosylmethionine?

6. [2-3H] Acetic acid is prochiral. Label the pro-S and pro-R atoms on this molecule.

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